Brief Information of the Compound and Protein
Compound Name
N-[[4-(6-aminopyrimidin-4-yl)-2-methylphenyl]methyl]-2-tert-butyl-1,3-thiazole-5-carboxamide
    Show/Hide
Canonical SMILES
Cc1cc(ccc1CNC(=O)c1cnc(s1)C(C)(C)C)-c1cc(N)ncn1
    Show/Hide
Compound Formula C20H23N5OS
Compound Structure
Protein Name
Tyrosine-protein kinase BTK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Tec family
Uniprot ID
Q06187
Gene Name
BTK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 9 nM
   TI
   LI
   LO
   TS