Brief Information of the Compound and Protein
Compound Name
 Compound Info 
methyl 4-[[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]carbamoyl]-2-(quinoline-2-carbonylamino)benzoate
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 PubChem ID
CID: 25222999
SID: 57573427
Canonical SMILES
COC(=O)c1ccc(cc1NC(=O)c1ccc2ccccc2n1)C(=O)Nc1ccc(CCN2CCc3cc(OC)c(OC)cc3C2)cc1
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Compound Formula C38H36N4O6
Compound Structure
Protein Name
 Protein Info 
ATP-dependent translocase ABCB1
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000356 KB-V1
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 >= 12080 nM
   TI
   LI
   LO
   TS
2
IC50 > 29000 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
EC50 = 105 nM
   TI
   LI
   LO
   TS
2
IC50 = 294 nM
   TI
   LI
   LO
   TS