Brief Information of the Compound and Protein
Compound Name
3-[2-(3,4-dichlorophenyl)ethylamino]-N-[2-[2-(5-hydroxy-3-oxo-4H-1,4-benzoxazin-8-yl)ethylamino]ethyl]-N-methylpropanamide
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Canonical SMILES
CN(CCNCCc1ccc(O)c2NC(=O)COc12)C(=O)CCNCCc1ccc(Cl)c(Cl)c1
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Compound Formula C24H30Cl2N4O4
Compound Structure
Protein Name
N-lysine methyltransferase SMYD2
Protein Classification
Epigenetic regulator
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Writer
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Protein methyltransferase
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SET domain
Uniprot ID
Q9NRG4
Gene Name
SMYD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  2
1
IC50 = 9980 nM
   TI
   LI
   LO
   TS
2
IC50 = 23590 nM
   TI
   LI
   LO
   TS