Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-[2-[4-[2-(1H-indol-3-yl)ethyl]piperazin-1-yl]phenyl]-N-(3-pyrrolidin-1-ylpropyl)pyridine-3-carboxamide
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 PubChem ID
CID: 122705799
Canonical SMILES
O=C(NCCCN1CCCC1)c1cncc(c1)-c1ccccc1N1CCN(CCc2c[nH]c3ccccc23)CC1
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Compound Formula C33H40N6O
Compound Structure
Protein Name
 Protein Info 
N-lysine methyltransferase SMYD2
Protein Classification
Epigenetic regulator
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Writer
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Protein methyltransferase
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SET domain
Uniprot ID
Q9NRG4
Gene Name
SMYD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 1020 nM
   TI
   LI
   LO
   TS
2
IC50 = 2430 nM
   TI
   LI
   LO
   TS
3
IC50 = 13260 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 17 nM