Brief Information of the Compound and Protein
Compound Name
1-[4-(4-amino-7-propan-2-ylpyrrolo[2,3-d]pyrimidine-5-carbonyl)pyridin-2-yl]-3-(2,4-difluorophenyl)urea
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PubChem ID
CID: 68904737
Canonical SMILES
CC(C)n1cc(C(=O)c2ccnc(NC(=O)Nc3ccc(F)cc3F)c2)c2c(N)ncnc12
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Compound Formula C22H19F2N7O2
Compound Structure
Protein Name
BDNF/NT-3 growth factors receptor
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase Trk family
Uniprot ID
Q16620
Gene Name
NTRK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  1
1
IC50 = 5 nM
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