Brief Information of the Compound and Protein
Compound Name
N-[5-[2-amino-7-(1-hydroxy-2-methylpropan-2-yl)pyrrolo[2,3-d]pyrimidine-5-carbonyl]pyridin-3-yl]-2-(4-chlorophenyl)acetamide
    Show/Hide
PubChem ID
CID: 66571443
SID: 152229215
Canonical SMILES
CC(C)(CO)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(Cl)cc3)c2)c2cnc(N)nc12
    Show/Hide
Compound Formula C24H23ClN6O3
Compound Structure
Protein Name
BDNF/NT-3 growth factors receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Trk family
Uniprot ID
Q16620
Gene Name
NTRK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  1
1
IC50 = 2 nM
   TI
   LI
   LO
   TS