Brief Information of the Compound and Protein
Compound Name
US8846698, 71
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PubChem ID
CID: 70847539
Canonical SMILES
CC(C)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(cc3)C#N)c2)c2cncnc12
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Compound Formula C24H20N6O2
Compound Structure
Protein Name
BDNF/NT-3 growth factors receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
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TK protein kinase group
>
Tyrosine protein kinase Trk family
Uniprot ID
Q16620
Gene Name
NTRK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  1
1
IC50 = 42 nM
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