Brief Information of the Compound and Protein
Compound Name
N-[4-[(E)-2-[4-(4-Methylpiperazin-1-yl)-6-[[5-(oxetan-3-yl)-1H-pyrazol-3-yl]amino]pyrimidin-2-yl]ethenyl]phenyl]prop-2-enamide
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Canonical SMILES
C=CC(=O)Nc1ccc(/C=C/c2nc(Nc3cc(C4COC4)[nH]n3)cc(N3CCN(C)CC3)n2)cc1
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Compound Formula C26H30N8O2
Compound Structure
Protein Name
Fibroblast growth factor receptor 3
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase FGFR family
Uniprot ID
P22607
Gene Name
FGFR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
GI50 = 5.8 nM
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