Brief Information of the Compound and Protein
Compound Name
N-[4-(2-[4-[(5-Methyl-1H-pyrazol-3-yl)amino]-6-(4-methylpiperazin-1-yl)pyrimidin-2-yl]ethyl)phenyl]prop-2-enamide
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Canonical SMILES
C=CC(=O)Nc1ccc(CCc2nc(Nc3cc(C)[nH]n3)cc(N3CCN(C)CC3)n2)cc1
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Compound Formula C24H30N8O
Compound Structure
Protein Name
Fibroblast growth factor receptor 3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P22607
Gene Name
FGFR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
GI50 = 55 nM
   TI
   LI
   LO
   TS
2
GI50 = 66 nM
   TI
   LI
   LO
   TS