Brief Information of the Compound and Protein
Compound Name
N-(4-(2-(6-(5-methyl-1H-pyrazol-3-ylamino)-2-(4-methylpiperazin-1-yl)pyrimidin-4-yl)vinyl)phenyl)acrylamide
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Canonical SMILES
C=CC(=O)Nc1ccc(/C=C/c2cc(Nc3cc(C)[nH]n3)nc(N3CCN(C)CC3)n2)cc1
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Compound Formula C24H28N8O
Compound Structure
Protein Name
Fibroblast growth factor receptor 3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P22607
Gene Name
FGFR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
GI50 = 42 nM
   TI
   LI
   LO
   TS
2
GI50 = 46 nM
   TI
   LI
   LO
   TS