Brief Information of the Compound and Protein
Compound Name
N-[4-[(E)-2-[4-(4-methylpiperazin-1-yl)-6-[(5-propan-2-yl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]ethenyl]phenyl]prop-2-enamide
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Canonical SMILES
CC(C)c1cc(Nc2cc(nc(\C=C\c3ccc(NC(=O)C=C)cc3)n2)N2CCN(C)CC2)n[nH]1
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Compound Formula C26H32N8O
Compound Structure
Protein Name
Fibroblast growth factor receptor 4
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase FGFR family
Uniprot ID
P22455
Gene Name
FGFR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
GI50 = 6.4 nM
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