Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-[(4R,9aS)-4-methyl-8-(1,2,3,4-tetrahydroisoquinolin-5-yl)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-2-yl]quinoline-8-carbonitrile
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 PubChem ID
CID: 155192028
Canonical SMILES
C[C@@H]1CN(C[C@@H]2CN(CCN12)c1cccc2CNCCc12)c1ccc(C#N)c2ncccc12
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Compound Formula C27H30N6
Compound Structure
Protein Name
 Protein Info 
Toll-like receptor 7
Protein Classification
Membrane receptor
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Toll-like and Il-1 receptors
Uniprot ID
Q9NYK1
Gene Name
TLR7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000686 HEK-Blue hTLR7
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 7 nM
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