Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[2-[1-(2-cyanoacetyl)azetidin-3-yl]-6-(2-hydroxypropan-2-yl)indazol-5-yl]-6-(trifluoromethyl)pyridine-2-carboxamide
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Canonical SMILES
CC(C)(O)c1cc2nn(cc2cc1NC(=O)c1cccc(n1)C(F)(F)F)C1CN(C1)C(=O)CC#N
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Compound Formula C23H21F3N6O3
Compound Structure
Protein Name
 Protein Info 
Interleukin-1 receptor-associated kinase 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase IRAK family
Uniprot ID
Q9NWZ3
Gene Name
IRAK4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 > 2000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 36.7 nM