Brief Information of the Compound and Protein
Compound Name
N-[2-[2-(dimethylamino)ethyl]-6-(2-hydroxypropan-2-yl)indazol-5-yl]-2-(2-methylpyridin-4-yl)-1,3-oxazole-4-carboxamide
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Canonical SMILES
CN(C)CCn1cc2cc(NC(=O)c3coc(n3)-c3ccnc(C)c3)c(cc2n1)C(C)(C)O
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Compound Formula C24H28N6O3
Compound Structure
Protein Name
Interleukin-1 receptor-associated kinase 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
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TKL protein kinase IRAK family
Uniprot ID
Q9NWZ3
Gene Name
IRAK4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 58.7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7.7 nM