Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[2-(1-ethylsulfonylazetidin-3-yl)-6-(2-hydroxypropan-2-yl)indazol-5-yl]-6-(trifluoromethyl)pyridine-2-carboxamide
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Canonical SMILES
CCS(=O)(=O)N1CC(C1)n1cc2cc(NC(=O)c3cccc(n3)C(F)(F)F)c(cc2n1)C(C)(C)O
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Compound Formula C22H24F3N5O4S
Compound Structure
Protein Name
 Protein Info 
Interleukin-1 receptor-associated kinase 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase IRAK family
Uniprot ID
Q9NWZ3
Gene Name
IRAK4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 256 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 57 nM