Brief Information of the Compound and Protein
Compound Name
N-[5-[[(3S,5S)-3-(2,6-dimethylpyridin-4-yl)oxy-1-oxa-7-azaspiro[4.4]nonan-7-yl]methyl]-1,3-thiazol-2-yl]acetamide
    Show/Hide
Canonical SMILES
CC(=O)Nc1ncc(CN2CC[C@]3(C[C@@H](CO3)Oc3cc(C)nc(C)c3)C2)s1
    Show/Hide
Compound Formula C20H26N4O3S
Compound Structure
Protein Name
Protein O-GlcNAcase
Protein Classification
Enzyme
Uniprot ID
O60502
Gene Name
OGA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 537 nM
   TI
   LI
   LO
   TS