Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[2-cyclopropyl-1-(4-fluorophenyl)sulfonylspiro[2H-indole-3,4'-thiane]-5-yl]pyridine-3-carboxamide
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Canonical SMILES
Fc1ccc(cc1)S(=O)(=O)N1C(C2CC2)C2(CCSCC2)c2cc(NC(=O)c3cccnc3)ccc12
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Compound Formula C27H26FN3O3S2
Compound Structure
Protein Name
 Protein Info 
Gonadotropin-releasing hormone receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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GnRH receptor
Uniprot ID
P30968
Gene Name
GNRHR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 48 nM
   TI
   LI
   LO
   TS
2
IC50 = 132 nM
   TI
   LI
   LO
   TS