Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1'-acetyl-N-[(3-chloropyridin-2-yl)methyl]-1-(4-fluorophenyl)sulfonyl-2-methylspiro[2H-indole-3,4'-piperidine]-5-carboxamide
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Canonical SMILES
CC1N(c2ccc(cc2C11CCN(CC1)C(C)=O)C(=O)NCc1ncccc1Cl)S(=O)(=O)c1ccc(F)cc1
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Compound Formula C28H28ClFN4O4S
Compound Structure
Protein Name
 Protein Info 
Gonadotropin-releasing hormone receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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GnRH receptor
Uniprot ID
P30968
Gene Name
GNRHR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 35 nM
   TI
   LI
   LO
   TS
2
IC50 = 53.5 nM
   TI
   LI
   LO
   TS