Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3S)-3-cyclopropyl-3-[3-[[3-(5,5-dimethylcyclopenten-1-yl)-4-(2-fluoro-5-methoxyphenyl)phenyl]methoxy]phenyl]propanoic acid
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 PubChem ID
CID: 57706778
SID: 144077263
Canonical SMILES
COc1ccc(F)c(c1)-c1ccc(COc2cccc(c2)[C@@H](CC(O)=O)C2CC2)cc1C1=CCCC1(C)C
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Compound Formula C33H35FO4
Compound Structure
Protein Name
 Protein Info 
Free fatty acid receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
Free fatty acid receptor
Uniprot ID
O14842
Gene Name
FFAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000398 A-9
 Cell Line Info 
Mus musculus (Mouse)  1
1
EC50 = 13 nM
   TI
   LI
   LO
   TS
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  5
1
EC50 = 150 nM
   TI
   LI
   LO
   TS
2
EC50 = 160 nM
   TI
   LI
   LO
   TS
3
EC50 = 161 nM
   TI
   LI
   LO
   TS
4
EC50 = 710 nM
   TI
   LI
   LO
   TS
5
Kd = 5 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 3.5 nM
   TI
   LI
   LO
   TS
2
EC50 = 130 nM
   TI
   LI
   LO
   TS
3
EC50 = 392 nM
   TI
   LI
   LO
   TS