Brief Information of the Compound and Protein
Compound Name
N-(2-morpholin-4-yl-5-piperidin-1-yl-[1,3]oxazolo[4,5-b]pyridin-6-yl)-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide
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PubChem ID
CID: 118224451
Canonical SMILES
O=C(Nc1cc2oc(nc2nc1N1CCCCC1)N1CCOCC1)c1cccc(n1)-c1cn[nH]c1
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Compound Formula C24H26N8O3
Compound Structure
Protein Name
Interleukin-1 receptor-associated kinase 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase IRAK family
Uniprot ID
Q9NWZ3
Gene Name
IRAK4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 10.3 nM
   TI
   LI
   LO
   TS
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 102.5 nM
   TI
   LI
   LO
   TS