Brief Information of the Compound and Protein
Compound Name
2-chloro-N-(3-chloro-4-methoxyphenyl)-2,2-difluoro-N-[2-oxo-2-(2-phenylethylamino)-1-thiophen-2-ylethyl]acetamide
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Canonical SMILES
COc1ccc(cc1Cl)N(C(C(=O)NCCc1ccccc1)c1cccs1)C(=O)C(F)(F)Cl
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Compound Formula C23H20Cl2F2N2O3S
Compound Structure
Protein Name
Phospholipid hydroperoxide glutathione peroxidase GPX4
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P36969
Gene Name
GPX4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000561 LOX-IMVI Homo sapiens (Human)  1
1
EC50 > 33000 nM
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