Brief Information of the Compound and Protein
Compound Name
1-[4-[bis(4-chlorophenyl)methyl]piperazin-1-yl]prop-2-yn-1-one
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Canonical SMILES
Clc1ccc(cc1)C(N1CCN(CC1)C(=O)C#C)c1ccc(Cl)cc1
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Compound Formula C20H18Cl2N2O
Compound Structure
Protein Name
Phospholipid hydroperoxide glutathione peroxidase GPX4
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P36969
Gene Name
GPX4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000561 LOX-IMVI Homo sapiens (Human)  2
1
EC50 = 1200 nM
   TI
   LI
   LO
   TS
2
EC50 = 3600 nM
   TI
   LI
   LO
   TS