Brief Information of the Compound and Protein
Compound Name
2-(N-(2-bromoacetyl)-3-chloro-4-methoxyanilino)-N-(2-phenylethyl)-2-thiophen-2-ylacetamide
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Canonical SMILES
COc1ccc(cc1Cl)N(C(C(=O)NCCc1ccccc1)c1cccs1)C(=O)CBr
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Compound Formula C23H22BrClN2O3S
Compound Structure
Protein Name
Phospholipid hydroperoxide glutathione peroxidase GPX4
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P36969
Gene Name
GPX4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000561 LOX-IMVI Homo sapiens (Human)  2
1
EC50 = 600 nM
   TI
   LI
   LO
   TS
2
EC50 = 5200 nM
   TI
   LI
   LO
   TS