Brief Information of the Compound and Protein
Compound Name
[4-[bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone
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PubChem ID
CID: 49766530
SID: 140105830
Canonical SMILES
Cc1onc(C(=O)N2CCN(CC2)C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)c1[N+]([O-])=O
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Compound Formula C22H20Cl2N4O4
Compound Structure
Protein Name
Phospholipid hydroperoxide glutathione peroxidase GPX4
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P36969
Gene Name
GPX4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000561 LOX-IMVI Homo sapiens (Human)  2
1
EC50 = 44 nM
   TI
   LI
   LO
   TS
2
EC50 > 33000 nM
   TI
   LI
   LO
   TS