Brief Information of the Compound and Protein
Compound Name
 Compound Info 
methyl (E)-4-[4-[bis(4-chlorophenyl)methyl]piperazin-1-yl]-4-oxobut-2-enoate
    Show/Hide
Canonical SMILES
COC(=O)\C=C\C(=O)N1CCN(CC1)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1
    Show/Hide
Compound Formula C22H22Cl2N2O3
Compound Structure
Protein Name
 Protein Info 
Phospholipid hydroperoxide glutathione peroxidase GPX4
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P36969
Gene Name
GPX4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000561 LOX-IMVI
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 18000 nM
   TI
   LI
   LO
   TS
2
EC50 = 19000 nM
   TI
   LI
   LO
   TS