Brief Information of the Compound and Protein
Compound Name
7-chloro-1-(1-pyridin-2-ylpiperidin-4-yl)-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
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Canonical SMILES
Clc1ccc-2c(CCc3nnc(C4CCN(CC4)c4ccccn4)n-23)c1
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Compound Formula C20H20ClN5
Compound Structure
Protein Name
Vasopressin V1a receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Vasopressin and oxytocin receptor
Uniprot ID
P37288
Gene Name
AVPR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1 Homo sapiens (Human)  2
1
IC50 = 1400 nM
   TI
   LI
   LO
   TS
2
Ki = 71 nM
   TI
   LI
   LO
   TS