Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(4R,5S)-4-cyclopropyl-3,9-dioxo-7-oxa-2,10,17,19,23-pentazatetracyclo[16.3.1.12,5.112,16]tetracosa-1(22),12(23),13,15,18,20-hexaene-4-carbonitrile
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 PubChem ID
CID: 156011795
Canonical SMILES
O=C1N2C[C@@H](COCC(=O)NCc3cccc(Nc4cc2ccn4)n3)[C@@]1(C#N)C1CC1
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Compound Formula C22H22N6O3
Compound Structure
Protein Name
 Protein Info 
Non-receptor tyrosine-protein kinase TYK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
P29597
Gene Name
TYK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1300 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 130 nM