Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(4R,5S,9Z)-4-cyclopropyl-3-oxo-7,12-dioxa-2,19,21,25-tetrazatetracyclo[18.3.1.12,5.114,18]hexacosa-1(24),9,14(25),15,17,20,22-heptaene-4-carbonitrile
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 PubChem ID
CID: 156017814
Canonical SMILES
O=C1N2C[C@@H](COC\C=C/COCc3cccc(Nc4cc2ccn4)n3)[C@@]1(C#N)C1CC1
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Compound Formula C24H25N5O3
Compound Structure
Protein Name
 Protein Info 
Non-receptor tyrosine-protein kinase TYK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
P29597
Gene Name
TYK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 260 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5.2 nM