Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(4R,5S)-4-cyclopropyl-3-oxo-7,12-dioxa-2,19,21,25-tetrazatetracyclo[18.3.1.12,5.114,18]hexacosa-1(24),14(25),15,17,20,22-hexaene-4-carbonitrile
    Show/Hide
 PubChem ID
CID: 156018413
Canonical SMILES
O=C1N2C[C@@H](COCCCCOCc3cccc(Nc4cc2ccn4)n3)[C@@]1(C#N)C1CC1
    Show/Hide
Compound Formula C24H27N5O3
Compound Structure
Protein Name
 Protein Info 
Non-receptor tyrosine-protein kinase TYK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
P29597
Gene Name
TYK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 210 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4.9 nM