Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}pyrrolidine-2-carbonitrile
    Show/Hide
 PubChem ID
CID: 6918537
SID: 14898545
Canonical SMILES
OC12CC3CC(C1)CC(C3)(C2)NCC(=O)N1CCC[C@H]1C#N
    Show/Hide
Compound Formula C17H25N3O2
Compound Structure
Protein Name
 Protein Info 
Prolyl endopeptidase FAP
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease SC clan
>
Serine protease S9B subfamily
Uniprot ID
Q12884
Gene Name
FAP
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000023 BTI-Tn-5B1-4
 Cell Line Info 
Trichoplusia ni (Cabbage looper)  1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CL000102 U-87MG ATCC
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 79760 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 52000 nM
2 IC50 = 73000 nM
3 IC50 > 20000 nM
4 IC50 > 100000 nM