Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-2-(4-(3-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)propyl)benzamido)pentanedioic acid
    Show/Hide
 PubChem ID
CID: 135800109
SID: 49630906
Canonical SMILES
Nc1nc2[nH]c(CCCc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cc2c(=O)[nH]1
    Show/Hide
Compound Formula C21H23N5O6
Compound Structure
Protein Name
 Protein Info 
Trifunctional purine biosynthetic protein adenosine-3
Protein Classification
Enzyme
>
Ligase
Uniprot ID
P22102
Gene Name
GART
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000220 KB
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 1.7 nM
   TI
   LI
   LO
   TS
2
IC50 = 18 nM
   TI
   LI
   LO
   TS
3
IC50 > 1000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 160 nM