Brief Information of the Compound and Protein
Compound Name
(3S)-1-[4-chloro-3-(trifluoromethyl)phenyl]pyrrolidine-3-carboxylic acid
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PubChem ID
CID: 154585553
Canonical SMILES
OC(=O)[C@H]1CCN(C1)c1ccc(Cl)c(c1)C(F)(F)F
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Compound Formula C12H11ClF3NO2
Compound Structure
Protein Name
Palmitoleoyl-protein carboxylesterase NOTUM
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q6P988
Gene Name
NOTUM
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 110 nM
   TI
   LI
   LO
   TS
CL000970 HEK293S GnTI- Homo sapiens (Human)  1
1
IC50 = 110 nM
   TI
   LI
   LO
   TS