Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-[2-(4-cyclobutylpiperazin-1-yl)quinazolin-6-yl]-1-methylpyridin-2-one
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 PubChem ID
CID: 156021083
Canonical SMILES
Cn1cc(ccc1=O)-c1ccc2nc(ncc2c1)N1CCN(CC1)C1CCC1
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Compound Formula C22H25N5O
Compound Structure
Protein Name
 Protein Info 
Toll-like receptor 9
Protein Classification
Membrane receptor
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Toll-like and Il-1 receptors
Uniprot ID
Q9NR96
Gene Name
TLR9
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 2200 nM
   TI
   LI
   LO
   TS