Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-chloro-5-[(4S)-5,5-difluoro-4-hydroxy-3-methylsulfonyl-4,6-dihydrocyclopenta[c]thiophen-1-yl]benzonitrile
    Show/Hide
 PubChem ID
CID: 153363378
Canonical SMILES
CS(=O)(=O)c1sc(c2CC(F)(F)[C@@H](O)c12)-c1cc(Cl)cc(c1)C#N
    Show/Hide
Compound Formula C15H10ClF2NO3S2
Compound Structure
Protein Name
 Protein Info 
Endothelial PAS domain-containing protein 1
Protein Classification
Transcription factor
Uniprot ID
Q99814
Gene Name
EPAS1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000244 786-O
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 < 50 nM