Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[trans-4-(3-Methyl-6-oxo-2,7-dihydropyrazolo[3,4-b]-pyridin-4-yl)cyclohexyl]cyclopentanecarboxamide
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Canonical SMILES
Cc1[nH]nc2[nH]c(=O)cc([C@H]3CC[C@H](NC(=O)C4CCCC4)CC3)c12
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Compound Formula C19H26N4O2
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase JAK1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
P23458
Gene Name
JAK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000743 CellSensor STAT6-bla RA-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 9100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 110 nM