Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[(1R,2S,4R,5S)-5-(3-Methyl-6-oxo-1,2,7-triaza-2,7-dihydroinden-4-yl)-2-norbornanyl]acetonitrile
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 PubChem ID
CID: 156020207
Canonical SMILES
Cc1[nH]nc2[nH]c(=O)cc([C@H]3C[C@H]4C[C@@H]3C[C@H]4CC#N)c12
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Compound Formula C16H18N4O
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase JAK1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
P23458
Gene Name
JAK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000743 CellSensor STAT6-bla RA-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 2700 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 47 nM