Brief Information of the Compound and Protein
Compound Name
 Compound Info 
ABROCITINIB
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Canonical SMILES
CCCS(=O)(=O)N[C@H]1C[C@@H](N(C)c2ncnc3[nH]ccc23)C1
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Compound Formula C14H21N5O2S
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase JAK1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
P23458
Gene Name
JAK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000743 CellSensor STAT6-bla RA-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 180 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5.1 nM
2 IC50 = 29 nM