Brief Information of the Compound and Protein
Compound Name
4-cyclohexyl-3-methyl-2,7-dihydropyrazolo[3,4-b]pyridin-6-one
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PubChem ID
CID: 156012065
Canonical SMILES
Cc1[nH]nc2[nH]c(=O)cc(C3CCCCC3)c12
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Compound Formula C13H17N3O
Compound Structure
Protein Name
Tyrosine-protein kinase JAK1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
P23458
Gene Name
JAK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000743 CellSensor STAT6-bla RA-1 Homo sapiens (Human)  1
1
IC50 = 3700 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 130 nM