Brief Information of the Compound and Protein
Compound Name
4-[[6-amino-2-(2-methoxyethoxy)-8-oxo-7H-purin-9-yl]methyl]benzoic acid
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PubChem ID
CID: 58019867
Canonical SMILES
COCCOc1nc(N)c2[nH]c(=O)n(Cc3ccc(cc3)C(O)=O)c2n1
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Compound Formula C16H17N5O5
Compound Structure
Protein Name
Toll-like receptor 7
Protein Classification
Membrane receptor
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Toll-like and Il-1 receptors
Uniprot ID
P58681
Gene Name
TLR7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000014 RAW 264.7 Mus musculus (Mouse)  3
1
EC50 = 252 nM
   TI
   LI
   LO
   TS
2
EC50 = 2110 nM
   TI
   LI
   LO
   TS
3
EC50 = 2150 nM
   TI
   LI
   LO
   TS