Brief Information of the Compound and Protein
Compound Name
N-(4-((2S,6R)-2,6-dimethylmorpholino)phenyl)-6-(1H-indazol-6-yl)imidazo[1,2-a]pyrazin-8-amine
    Show/Hide
PubChem ID
CID: 59473079
Canonical SMILES
C[C@@H]1CN(c2ccc(Nc3nc(-c4ccc5cn[nH]c5c4)cn4ccnc34)cc2)C[C@H](C)O1
    Show/Hide
Compound Formula C25H25N7O
Compound Structure
Protein Name
Tyrosine-protein kinase SYK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Syk family
Uniprot ID
P43405
Gene Name
SYK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos Homo sapiens (Human)  1
1
EC50 = 45 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4.9 nM