Brief Information of the Compound and Protein
Compound Name
6-(1H-indazol-6-yl)-N-(4-(tetrahydro-1H-furo[3,4-c]pyrrol-5(3H)-yl)phenyl)imidazo[1,2-a]pyrazin-8-amine
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PubChem ID
CID: 156011476
Canonical SMILES
c1cn2cc(-c3ccc4cn[nH]c4c3)nc(Nc3ccc(N4CC5COCC5C4)cc3)c2n1
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Compound Formula C25H23N7O
Compound Structure
Protein Name
Tyrosine-protein kinase SYK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Syk family
Uniprot ID
P43405
Gene Name
SYK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos Homo sapiens (Human)  1
1
EC50 = 187 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 9.6 nM