Brief Information of the Compound and Protein
Compound Name
N-(4-((1s,5s)-3,7-dioxa-9-azabicyclo[3.3.1]nonan-9-yl)phenyl)-6-(1H-indazol-6-yl)imidazo[1,2-a]pyrazin-8-amine
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Canonical SMILES
c1cn2cc(-c3ccc4cn[nH]c4c3)nc(Nc3ccc(N4[C@H]5COC[C@@H]4COC5)cc3)c2n1
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Compound Formula C25H23N7O2
Compound Structure
Protein Name
Tyrosine-protein kinase SYK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Syk family
Uniprot ID
P43405
Gene Name
SYK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos Homo sapiens (Human)  1
1
EC50 = 33 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 13.7 nM