Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-(1H-indazol-6-yl)-N-[4-(2-oxa-6-azaspiro[3.3]heptan-6-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine
    Show/Hide
 PubChem ID
CID: 46234930
SID: 96095519
Canonical SMILES
C1OCC11CN(C1)c1ccc(Nc2nc(cn3ccnc23)-c2ccc3cn[nH]c3c2)cc1
    Show/Hide
Compound Formula C24H21N7O
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase SYK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Syk family
Uniprot ID
P43405
Gene Name
SYK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 63 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5 nM