Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[4-(1,1-dioxo-1,4-thiazinan-4-yl)phenyl]-6-(1H-indazol-6-yl)imidazo[1,2-a]pyrazin-8-amine
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 PubChem ID
CID: 59473104
Canonical SMILES
O=S1(=O)CCN(CC1)c1ccc(Nc2nc(cn3ccnc23)-c2ccc3cn[nH]c3c2)cc1
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Compound Formula C23H21N7O2S
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase SYK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Syk family
Uniprot ID
P43405
Gene Name
SYK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 33 nM
   TI
   LI
   LO
   TS
2
EC50 = 40 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.1 nM
2 IC50 = 19.5 nM