Brief Information of the Compound and Protein
Compound Name
[(3R)-1-azabicyclo[2.2.2]octan-3-yl] N-[2-(3-chlorophenyl)-4-fluorophenyl]carbamate
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PubChem ID
CID: 156021744
Canonical SMILES
Fc1ccc(NC(=O)O[C@H]2CN3CCC2CC3)c(c1)-c1cccc(Cl)c1
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Compound Formula C20H20ClFN2O2
Compound Structure
Protein Name
Muscarinic acetylcholine receptor M3
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Acetylcholine receptor
Uniprot ID
P20309
Gene Name
CHRM3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
Ki = 0.39 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 17 nM
   TI
   LI
   LO
   TS
2
EC50 = 27 nM
   TI
   LI
   LO
   TS