Brief Information of the Compound and Protein
Compound Name
2-(4-(3-fluoro-3-(trifluoromethyl)-1,3'-biazetidine-1'-carbonyl)-5-methyl-1H-pyrazol-1-yl)pyrrolo[1,2-f][1,2,4]triazin-4(3H)-one
    Show/Hide
PubChem ID
CID: 137049515
Canonical SMILES
Cc1c(C(=O)N2CC(N3CC(F)(C(F)(F)F)C3)C2)cnn1-c1nn2cccc2c(=O)[nH]1
    Show/Hide
Compound Formula C18H17F4N7O2
Compound Structure
Protein Name
Sepiapterin reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P35270
Gene Name
SPR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000151 SK-N-BE(2) Homo sapiens (Human)  1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS