Brief Information of the Compound and Protein
Compound Name
2-(4-(6,6-difluoro-2-azaspiro[3.3]heptane-2-carbonyl)-5-methyl-1H-pyrazol-1-yl)-6,7-dihydro-3H-cyclopenta[d]pyrimidin-4(5H)-one
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PubChem ID
CID: 137049560
Canonical SMILES
Cc1c(C(=O)N2CC3(C2)CC(F)(F)C3)cnn1-c1nc2c(c(=O)[nH]1)CCC2
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Compound Formula C18H19F2N5O2
Compound Structure
Protein Name
Sepiapterin reductase
Protein Classification
Enzyme
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Oxidoreductase
Uniprot ID
P35270
Gene Name
SPR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000151 SK-N-BE(2) Homo sapiens (Human)  1
1
IC50 = 700 nM
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