Brief Information of the Compound and Protein
Compound Name
2-(5-methyl-4-(3-oxo-4-(2,2,2-trifluoroethyl)piperazine-1-carbonyl)-1H-pyrazol-1-yl)pyrrolo[1,2-f][1,2,4]triazin-4(3H)-one
    Show/Hide
PubChem ID
CID: 137049533
Canonical SMILES
Cc1c(C(=O)N2CCN(CC(F)(F)F)C(=O)C2)cnn1-c1nn2cccc2c(=O)[nH]1
    Show/Hide
Compound Formula C17H16F3N7O3
Compound Structure
Protein Name
Sepiapterin reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P35270
Gene Name
SPR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000151 SK-N-BE(2) Homo sapiens (Human)  1
1
IC50 = 1300 nM
   TI
   LI
   LO
   TS