Brief Information of the Compound and Protein
Compound Name
6-methyl-2-[4-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)-1H-1,2,3-triazol-1-yl]-3,4-dihydropyrimidin-4-one
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PubChem ID
CID: 137129913
Canonical SMILES
Cc1cc(=O)[nH]c(-n2cc(C(=O)N3CCc4ccccc4C3)nn2)n1
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Compound Formula C17H16N6O2
Compound Structure
Protein Name
Sepiapterin reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P35270
Gene Name
SPR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000151 SK-N-BE(2) Homo sapiens (Human)  1
1
IC50 = 10000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 20 nM