Brief Information of the Compound and Protein
Compound Name
5-methyl-1-(4-oxo-4,5,6,7-tetrahydro-3H-cyclopenta[d]pyrimidin-2-yl)-N-phenethyl-N-(3,3,3-trifluoro-2-hydroxypropyl)-1H-pyrazole-4-carboxamide
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PubChem ID
CID: 137049203
Canonical SMILES
Cc1c(C(=O)N(CCc2ccccc2)CC(O)C(F)(F)F)cnn1-c1nc2c(c(=O)[nH]1)CCC2
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Compound Formula C23H24F3N5O3
Compound Structure
Protein Name
Sepiapterin reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P35270
Gene Name
SPR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000151 SK-N-BE(2) Homo sapiens (Human)  1
1
IC50 = 400 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 20 nM